Mentor:  Robert Hardy, Ph.D.
Undergraduate Institution: Ithaca College
Entered CMPh Program:  Fall 2004
Phone: 205.934.9926
Email:  lmevans@uab.edu

RESEARCH INTEREST

Stearate is an 18-carbon saturated fatty acid found in chocolate, red meat and partially hydrogenated vegetable oil.  Our laboratory demonstrated that stearate causes breast cancer cells to become anti-apoptotic, anti-proliferative, anti-migratory, and to de-adhere from the extracellular matrix.  Annexin II is a calcium dependent membrane binding protein that plays a role in cell proliferation, signaling pathways, extracellular matrix, regulation of proteolysis, and cholesterol transport.  Stearate causes a dramatic translocation of annexin II to lipid rafts in breast cancer cells.  The role of my project is to determine and characterize the functional effects of this translocation.

About Lynda:

I graduated in 2003 with a B.A. in Biology from Ithaca College in Ithaca, NY.  In my spare time I like to read, play softball, hang out with my friends, take random trips around the South, visit my family, and volunteer with various groups at my church. 

"Me and Nana"	"Grace, Me and Kristin"

LHRB 531
701 19th Street South
Birmingham, AL 35233